The dawn of bio-engineering changed the criminal landscape for the worse. Genetic modification and bio-organic weapons have revolutionized the black markets and gave rise to a new kind of criminal: The Geneticist. These "doctors" play god with the lives of millions of people. No longer are gangs limited by their own poor abilities or intellect. If they can pay, they get equipped with the latest in genetic and cybernetic advancements.
This process is of course highly illegal, but since when has that ever stopped criminals from doing what they do? They are criminals after all. Genetically enhanced criminals overpower the police already, but their growing numbers make matters worse than they already are.
What these dark times need are heroes that are not afraid to fight back, that go to the ends of the earth to save us. But how desperate must a man be if he risked losing it all to fight back? Only if you have already lost everything, you have nothing left to lose...